pathhunter detection kit Search Results


90
DiscoverX corporation pathhunter chemiluminescence detection reagents
Pathhunter Chemiluminescence Detection Reagents, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pathhunter chemiluminescence detection reagents - by Bioz Stars, 2026-10
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DiscoverX corporation pathhunter detection reagent cocktail
Pathhunter Detection Reagent Cocktail, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pathhunter detection reagent cocktail - by Bioz Stars, 2026-10
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DiscoverX corporation pathhunter® flash detection kit
Pathhunter® Flash Detection Kit, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pathhunter® flash detection kit - by Bioz Stars, 2026-10
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DiscoverX corporation pathhunter prolabel protein expression assay
Pathhunter Prolabel Protein Expression Assay, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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DiscoverX corporation pathhunter detection kit containing cell membrane permeabilizing reagent and beta-gal substrate
Pathhunter Detection Kit Containing Cell Membrane Permeabilizing Reagent And Beta Gal Substrate, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pathhunter detection kit containing cell membrane permeabilizing reagent and beta-gal substrate - by Bioz Stars, 2026-10
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90
DiscoverX corporation 12 μl/well detection reagent (pathhunter detection kit
12 μl/Well Detection Reagent (Pathhunter Detection Kit, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
12 μl/well detection reagent (pathhunter detection kit - by Bioz Stars, 2026-10
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DiscoverX corporation pathhunter bioassay
Pathhunter Bioassay, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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DiscoverX corporation chemiluminiescent pathhunter flash detection kit
Chemiluminiescent Pathhunter Flash Detection Kit, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DiscoverX corporation pathhunter detection kit 93e0001
Pathhunter Detection Kit 93e0001, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pathhunter detection kit 93e0001 - by Bioz Stars, 2026-10
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DiscoverX corporation lysis buffer from the pathhunter detection kit
Lysis Buffer From The Pathhunter Detection Kit, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DiscoverX corporation β-gal substrate pathhunter efc detection kit
β Gal Substrate Pathhunter Efc Detection Kit, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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86
Eurofins pathhunter detection kit
Characterization of SLC6A8 variants by trafficking and transport activity. (A) Schematic of assays developed to identify correctors of SLC6A8 with a trafficking assay to measure surface localization of SLC6A8 and a transport assay to measure creatine transport through SLC6A8 into the cell. (B,C) Trafficking assay measuring surface localized SLC6A8 and intracellular creatine levels detected by RapidFire mass spectrometry of SLC6A8 variants following transient transfection in the <t>PathHunter</t> MEM-EA U-2 OS cells lacking endogenous SLC6A8 (values represent means normalized to wildtype SLC6A8 calculated from n = 2 technical replicates with standard deviation). (D) Correlation between surface localization and residual creatine transport of SLC6A8 variants profiled in (B,C). (E) Residual creatine transport in knock-in variants (values represent mean SLC6A8 knock-in variant as a percentage of wildtype SLC6A8 calculated from n = 3 technical replicates with standard deviation).
Pathhunter Detection Kit, supplied by Eurofins, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pathhunter+detection+kit/detection+kit+pathhunter/pmc11574759-152-18-21
Average 86 stars, based on 1 article reviews
pathhunter detection kit - by Bioz Stars, 2026-10
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Image Search Results


Characterization of SLC6A8 variants by trafficking and transport activity. (A) Schematic of assays developed to identify correctors of SLC6A8 with a trafficking assay to measure surface localization of SLC6A8 and a transport assay to measure creatine transport through SLC6A8 into the cell. (B,C) Trafficking assay measuring surface localized SLC6A8 and intracellular creatine levels detected by RapidFire mass spectrometry of SLC6A8 variants following transient transfection in the PathHunter MEM-EA U-2 OS cells lacking endogenous SLC6A8 (values represent means normalized to wildtype SLC6A8 calculated from n = 2 technical replicates with standard deviation). (D) Correlation between surface localization and residual creatine transport of SLC6A8 variants profiled in (B,C). (E) Residual creatine transport in knock-in variants (values represent mean SLC6A8 knock-in variant as a percentage of wildtype SLC6A8 calculated from n = 3 technical replicates with standard deviation).

Journal: ACS Chemical Biology

Article Title: Novel Corrector for Variants of SLC6A8: A Therapeutic Opportunity for Creatine Transporter Deficiency

doi: 10.1021/acschembio.4c00571

Figure Lengend Snippet: Characterization of SLC6A8 variants by trafficking and transport activity. (A) Schematic of assays developed to identify correctors of SLC6A8 with a trafficking assay to measure surface localization of SLC6A8 and a transport assay to measure creatine transport through SLC6A8 into the cell. (B,C) Trafficking assay measuring surface localized SLC6A8 and intracellular creatine levels detected by RapidFire mass spectrometry of SLC6A8 variants following transient transfection in the PathHunter MEM-EA U-2 OS cells lacking endogenous SLC6A8 (values represent means normalized to wildtype SLC6A8 calculated from n = 2 technical replicates with standard deviation). (D) Correlation between surface localization and residual creatine transport of SLC6A8 variants profiled in (B,C). (E) Residual creatine transport in knock-in variants (values represent mean SLC6A8 knock-in variant as a percentage of wildtype SLC6A8 calculated from n = 3 technical replicates with standard deviation).

Article Snippet: Luminescence indicative of SLC6A8 CTD mutant cell surface localization was measured according to the manufacturer’s protocol using the PathHunter Detection kit (Eurofins catalog no. 93-0001L) and an EnVision plate reader (PerkinElmer, 2104 multilabel reader).

Techniques: Activity Assay, Transport Assay, Mass Spectrometry, Transfection, Standard Deviation, Knock-In, Variant Assay